发明申请
- 专利标题： RENIN INHIBITORS
- 专利标题（中）： 雷宁抑制剂
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申请号： US12665198申请日： 2008-06-20
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公开(公告)号： US20100190829A1公开(公告)日： 2010-07-29
- 发明人: John J. Baldwin , Salvacion Cacatian , David A. Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Alexey V. Ishchenko , Lanqi Jia , Gerard McGeehan , Robert D. Simpson , Suresh B. Singh , Colin M. Tice , Zhenrong Xu , Jing Yuan , Wei Zhao
- 申请人： John J. Baldwin , Salvacion Cacatian , David A. Claremon , Lawrence W. Dillard , Patrick T. Flaherty , Alexey V. Ishchenko , Lanqi Jia , Gerard McGeehan , Robert D. Simpson , Suresh B. Singh , Colin M. Tice , Zhenrong Xu , Jing Yuan , Wei Zhao
- 专利权人： Vitae Pharmaceuticals Inc
- 当前专利权人： Vitae Pharmaceuticals Inc
- 国际申请： PCT/US08/07700 WO 20080620
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; C07D211/56 ; C07C271/20 ; A61K31/27 ; A61P9/12 ; A61P9/04 ; A61P27/06 ; A61P5/46 ; A61P25/22
摘要：
Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.
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