发明申请
US20100196311A1 METHODS AND COMPOSITIONS CONTAINING mTOR INHIBITORS FOR ENHANCING IMMUNE RESPONSES
审中-公开
含有mTOR抑制剂以增强免疫应答的方法和组合物
- 专利标题： METHODS AND COMPOSITIONS CONTAINING mTOR INHIBITORS FOR ENHANCING IMMUNE RESPONSES
- 专利标题（中）： 含有mTOR抑制剂以增强免疫应答的方法和组合物
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申请号： US12687650申请日： 2010-01-14
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公开(公告)号： US20100196311A1公开(公告)日： 2010-08-05
- 发明人: Hyung L. Kim , Protul Shrikant , YanPing Wang , Qingsheng Li , Rajesh Rao
- 申请人： Hyung L. Kim , Protul Shrikant , YanPing Wang , Qingsheng Li , Rajesh Rao
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; A61K39/00 ; A61K35/12 ; A61P35/00
摘要：
Provided are compositions and methods for enhancing immune responses to an antigen. The compositions contain an isolated population of CD8+T cells and an inhibitor of mammalian target of rapamycin (mTOR). The method for obtaining an enhanced immune response to an antigen in an individual entails administering to the individual the antigen and an inhibitor of mammalian target of rapamycin (mTOR). CD8+T cells may also be used for adoptive cell transfer (ACT) therapy.
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