发明申请
US20100196989A1 Alpha-Fetoprotein Immu31 Antibodies and Fusion Proteins and Methods of Use Thereof
有权
α-甲胎蛋白Immu31抗体和融合蛋白及其使用方法
- 专利标题: Alpha-Fetoprotein Immu31 Antibodies and Fusion Proteins and Methods of Use Thereof
- 专利标题(中): α-甲胎蛋白Immu31抗体和融合蛋白及其使用方法
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申请号: US12359745申请日: 2009-01-26
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公开(公告)号: US20100196989A1公开(公告)日: 2010-08-05
- 发明人: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- 申请人: Hans J. Hansen , Zhengxing Qu , David M. Goldenberg
- 申请人地址: US NJ Morris Plains
- 专利权人: IMMUNOMEDICS, INC.
- 当前专利权人: IMMUNOMEDICS, INC.
- 当前专利权人地址: US NJ Morris Plains
- 主分类号: C12N9/22
- IPC分类号: C12N9/22 ; C07K16/18 ; C07K19/00 ; C12N9/00 ; C12N9/16
摘要:
The present invention provides humanized, chimeric and human anti-alpha-fetoprotein antibodies, fusion proteins, and fragments thereof. The antibodies, fusion proteins, and fragments thereof, as well as combinations with other suitable antibodies, are useful for the treatment and diagnosis of hepatocellular carcinoma, hepatoblastoma, germ cell tumors carcinoma and other AFP-producing tumors.
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