Invention Application
US20100197673A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS
有权
作为细胞坏死因子抑制剂的吲哚和吲哚类化合物
- Patent Title: INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS
- Patent Title (中): 作为细胞坏死因子抑制剂的吲哚和吲哚类化合物
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Application No.: US12671038Application Date: 2008-08-18
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Publication No.: US20100197673A1Publication Date: 2010-08-05
- Inventor: Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Chul Woong Chung , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Hyo Shin Kwak , Dong Ook Seo , Eok Park
- Applicant: Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Chul Woong Chung , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Hyo Shin Kwak , Dong Ook Seo , Eok Park
- Applicant Address: KR Seoul
- Assignee: LG Life Sciences Ltd
- Current Assignee: LG Life Sciences Ltd
- Current Assignee Address: KR Seoul
- Priority: KR1020070082687 20070817
- International Application: PCT/KR2008/004784 WO 20080818
- Main IPC: A61K31/541
- IPC: A61K31/541 ; C07D401/02 ; A61K31/4439 ; C07D209/04 ; A61K31/404 ; A61K31/497 ; C07D417/14 ; C07D403/02 ; A61K31/496 ; C07D413/02 ; A61K31/5377 ; A61K31/454 ; C07D231/56 ; A61K31/416 ; A61P1/16 ; A61P25/00 ; A61P3/10 ; A61P31/00 ; A61P19/02 ; A61P35/00 ; A61P35/02 ; A61P11/00 ; A61P17/00
Abstract:
The present invention relates to indole or indazole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole or indazole compounds as an active ingredient.
Public/Granted literature
- US08436038B2 Indole and indazole compounds as an inhibitor of cellular necrosis Public/Granted day:2013-05-07
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