发明申请
US20100197908A1 Pyridazine Derivatives with MCH Antagonistic Activity and Medicaments Comprising These Compounds
审中-公开
具有MCH拮抗活性的哒嗪衍生物和包含这些化合物的药物
- 专利标题： Pyridazine Derivatives with MCH Antagonistic Activity and Medicaments Comprising These Compounds
- 专利标题（中）： 具有MCH拮抗活性的哒嗪衍生物和包含这些化合物的药物
-
申请号： US12518321申请日： 2007-12-10
-
公开(公告)号： US20100197908A1公开(公告)日： 2010-08-05
- 发明人: Thorsten Lehmann-Lintz , Dirk Stenkamp , Gerald Juergen Roth , Stephan Georg Mueller , Joerg Kley , Armin Heckel , Klaus Rudolf , Marcus Schindler , Ralf Lotz , Patrick Tielmann
- 申请人： Thorsten Lehmann-Lintz , Dirk Stenkamp , Gerald Juergen Roth , Stephan Georg Mueller , Joerg Kley , Armin Heckel , Klaus Rudolf , Marcus Schindler , Ralf Lotz , Patrick Tielmann
- 申请人地址： DE Ingelheim
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： DE Ingelheim
- 优先权： EP06125763.0 20061211
- 国际申请： PCT/EP2007/063575 WO 20071210
- 主分类号： C07D403/10
- IPC分类号： C07D403/10 ; C07D413/10 ; C07D401/10 ; C07D403/14 ; C07D401/14
摘要：
The present invention relates to compounds of general formula I wherein the groups and radicals B, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.
信息查询
