发明申请
US20100209400A1 TAK1-Mediated Regulation of Osteogenesis 审中-公开
TAK1介导的骨形成调节

TAK1-Mediated Regulation of Osteogenesis
摘要:
This invention is directed to methods, nucleic acids and compositions in TAK1-mediated regulation of SMAD activity. Promotion of TAK1 interaction with MH2 domains in SMADs negatively regulates SMAD biological activity. BMP-mediated SMAD activity is subject to TAK1 effects.
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