发明申请
US20100209532A1 TARGETED OXYGEN DELIVERY VIA INTRAVENOUS OR INTRA-ARTERIAL INFUSION OF OXYGENATED POLYMERIZED HEMOGLOBIN SOLUTIONS
审中-公开
通过氧化聚合的HEMOGLOBIN溶液的静脉内或腔内输注的目标氧气输送
- 专利标题： TARGETED OXYGEN DELIVERY VIA INTRAVENOUS OR INTRA-ARTERIAL INFUSION OF OXYGENATED POLYMERIZED HEMOGLOBIN SOLUTIONS
- 专利标题（中）： 通过氧化聚合的HEMOGLOBIN溶液的静脉内或腔内输注的目标氧气输送
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申请号： US12451997申请日： 2008-06-13
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公开(公告)号： US20100209532A1公开(公告)日： 2010-08-19
- 发明人: Gregory P. Dube , Zafiris W. Zafirelis , Anthony J. Laccetti , Javed Baqai
- 申请人： Gregory P. Dube , Zafiris W. Zafirelis , Anthony J. Laccetti , Javed Baqai
- 申请人地址： US MA Cambridge
- 专利权人： OPK BIOTECH LLC
- 当前专利权人： OPK BIOTECH LLC
- 当前专利权人地址： US MA Cambridge
- 国际申请： PCT/US2008/007445 WO 20080613
- 主分类号： A61K38/42
- IPC分类号： A61K38/42 ; A61K33/42 ; A61K33/06 ; A61K33/00 ; A61P9/10
摘要：
A method of delivering oxygen to a tissue, a blood vessel, an organ, or a region of an organ, under an ischemic condition, or prophylactically preventing occurrence of an ischemic condition, of a subject, comprising the step of administering to the subject an oxygenated hemoglobin solution, wherein the oxygenated hemoglobin solution includes polymerized hemoglobin, and wherein about 80% by weight, or greater, of the polymerized hemoglobin is oxyhemoglobin.
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