发明申请
- 专利标题： PREVENTIVE/REMEDY FOR CANCER
- 专利标题（中）： 预防/救治癌症
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申请号： US12738287申请日： 2008-10-15
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公开(公告)号： US20100210545A1公开(公告)日： 2010-08-19
- 发明人: Shinsuke Araki , Akira Hori , Yuusuke Nakayama
- 申请人： Shinsuke Araki , Akira Hori , Yuusuke Nakayama
- 优先权： JP2007-268433 20071015
- 国际申请： PCT/JP2008/069079 WO 20081015
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C12Q1/02
摘要：
The present invention provides identification of TRAIL signal activator sensitivity markers in cancer cells, and a method of diagnosing the sensitivity to TRAIL signal activator in a cancer patient using the markers. Tailor-made medical service of administering a TRAIL signal activator to a TRAIL signal activator sensitive cancer patient is provided.The present invention provides a preventive or remedy agent for cancer for a TRAIL signal activator sensitive patient, the agent comprising a TRAIL signal activator, wherein the patient is screened by using the fluctuation in the expression or activity of TRAIL signal activator sensitivity markers in a sample collected from a test subject, as an index. As the TRAIL signal activator sensitivity markers, AIM1, STK17B, LOC93349, CASP8 and the like may be mentioned.
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