发明申请
- 专利标题： Vaccine Nanotechnology
- 专利标题（中）： 疫苗纳米技术
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申请号： US12681814申请日： 2008-10-12
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公开(公告)号： US20100233251A1公开(公告)日： 2010-09-16
- 发明人: Ulrich H. Von Andrian , Omid C. Farokhzad , Robert S. Langer , Tobias Junt , Ashley Moseman , Liangfang Zhang , Pamela Basto , Matteo Iannacone , Frank Alexis
- 申请人： Ulrich H. Von Andrian , Omid C. Farokhzad , Robert S. Langer , Tobias Junt , Ashley Moseman , Liangfang Zhang , Pamela Basto , Matteo Iannacone , Frank Alexis
- 专利权人： Massachusetts Institute of Technology Massachusetts,President and Fellows of Harvard College Massachusetts,The Brigham and Women's Hospital ,Inc. Massachusetts,Immune Disease Institute Massachusetts
- 当前专利权人： Massachusetts Institute of Technology Massachusetts,President and Fellows of Harvard College Massachusetts,The Brigham and Women's Hospital ,Inc. Massachusetts,Immune Disease Institute Massachusetts
- 国际申请： PCT/US2008/011932 WO 20081012
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K9/14 ; A61K39/00
摘要：
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at least one targeting moiety and optionally at least one immunostimulatory agent. The invention provides pharmaceutical compositions comprising inventive vaccine nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive vaccine nanocarriers and pharmaceutical compositions thereof. The invention provides methods of prophylaxis and/or treatment of diseases, disorders, and conditions comprising administering at least one inventive vaccine nanocarrier to a subject in need thereof.
公开/授权文献
- US10736848B2 Vaccine nanotechnology 公开/授权日：2020-08-11
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