发明申请
- 专利标题： Transition metal catalyzed synthesis of 2H-indazoles
- 专利标题（中）： 过渡金属催化合成2H-吲唑
-
申请号： US12644371申请日： 2009-12-22
-
公开(公告)号： US20100234601A1公开(公告)日： 2010-09-16
- 发明人: Nis HALLAND , Marc NAZARE , Andreas LINDENSCHMIDT , Jorge ALONSO , Omar RKYEK , Matthias URMANN
- 申请人： Nis HALLAND , Marc NAZARE , Andreas LINDENSCHMIDT , Jorge ALONSO , Omar RKYEK , Matthias URMANN
- 申请人地址： FR Paris
- 专利权人： SANOFI-AVENTIS
- 当前专利权人： SANOFI-AVENTIS
- 当前专利权人地址： FR Paris
- 优先权： EP07290799.1 20070626
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D231/56 ; C07D401/06
摘要：
The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct transition metal catalyzed process to a wide variety of multifunctional 2H-indazoles or 2H-azaindazoles of the formula (I) from 2-halo-phenylacetylenes or (2-sulfonato)phenylacetylenes and monosubstituted hydrazines.
公开/授权文献
- US08283476B2 Transition metal catalyzed synthesis of 2H-indazoles 公开/授权日：2012-10-09