发明申请
- 专利标题： CHIMERIC NEWCASTLE DISEASE VIRUS VLPs
- 专利标题（中）： CHIMERIC NEWCASTLE病毒病毒VLP
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申请号： US12527844申请日： 2008-02-21
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公开(公告)号： US20100247574A1公开(公告)日： 2010-09-30
- 发明人: Kutub Mahmood , Gale Smith , Peter Pushko
- 申请人： Kutub Mahmood , Gale Smith , Peter Pushko
- 国际申请： PCT/US08/54570 WO 20080221
- 主分类号： A61K39/17
- IPC分类号： A61K39/17 ; C07K19/00 ; A61P31/14 ; C12P21/06
摘要：
The present invention discloses and claims chimeric virus like particles (VLPs) that express and/or contains Newcastle disease matrix protein. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising chimeric VLPs of the inventions. The invention also includes methods of making and administrating chimeric VLPs to vertebrates, including methods of inducing immunity to infections.
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