发明申请
- 专利标题： HEPATOCELLULAR CARCINOMA PROTEIN MARKER, AND METHOD FOR DETECTION OF HEPATOCELLULAR CARCINOMA USING THE SAME
- 专利标题（中）： 肝细胞癌蛋白标记物及使用其检测肝细胞癌的方法
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申请号： US12452216申请日： 2008-06-16
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公开(公告)号： US20100248256A1公开(公告)日： 2010-09-30
- 发明人: Hirotaka Minagawa , Kenji Miyazaki , Yo Tabuse , Kenichi Kamijo , Shuichi Kaneko
- 申请人： Hirotaka Minagawa , Kenji Miyazaki , Yo Tabuse , Kenichi Kamijo , Shuichi Kaneko
- 优先权： JP2007-162857 20070620
- 国际申请： PCT/JP2008/061375 WO 20080616
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07K14/435
摘要：
Provided are: a method of assessing hepatocellular carcinoma by using a protein with a different phosphorylated state in hepatocellular carcinoma cells compared with non-hepatocellular carcinoma cells; and a hepatocellular carcinoma protein marker for detecting hepatocellular carcinoma formed of the protein. The hepatocellular carcinoma protein marker for detecting hepatocellular carcinoma includes tumor rejection antigen gp96 formed of the amino acid represented by SEQ ID NO: 1, and is measured for its phosphorylated state to detect the presence or absence of hepatocellular carcinoma.
公开/授权文献
- US08207301B2 Hepatocellular carcinoma protein marker 公开/授权日：2012-06-26
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