发明申请
- 专利标题: ABCG2 INHIBITOR
- 专利标题(中): ABCG2抑制剂
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申请号: US12745899申请日: 2008-12-02
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公开(公告)号: US20100249089A1公开(公告)日: 2010-09-30
- 发明人: Ryuta Yamazaki , Hiroshi Hatano , Takashi Yaegashi , Yoshiaki Igarashi , Oh Yoshida , Yoshikazu Sugimoto
- 申请人: Ryuta Yamazaki , Hiroshi Hatano , Takashi Yaegashi , Yoshiaki Igarashi , Oh Yoshida , Yoshikazu Sugimoto
- 申请人地址: JP Tokyo
- 专利权人: KABUSHIKI KAISHA YAKULT HONSHA
- 当前专利权人: KABUSHIKI KAISHA YAKULT HONSHA
- 当前专利权人地址: JP Tokyo
- 优先权: JP2007-312176 20071203
- 国际申请: PCT/JP2008/003557 WO 20081202
- 主分类号: A61K31/4545
- IPC分类号: A61K31/4545 ; C07D409/14 ; A61K31/4535 ; A61K31/454 ; A61K31/496 ; A61K31/5377 ; A61P35/00
摘要:
The present invention relates to a breast cancer resistance protein (BCRP/ABCG2) inhibitor.The invention provides an acrylonitrile derivative represented by formula (1): (wherein A represents an optionally substituted 3- to 8-membered heterocyclic ring) or a salt thereof.