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    Anticancer agent sensitivity-determining marker
    2.
    发明授权
    Anticancer agent sensitivity-determining marker 有权
    抗癌剂灵敏度决定标记

    公开(公告)号：US08809362B2

    公开(公告)日：2014-08-19

    申请号：US13505175

    申请日：2010-10-29

    申请人： Yusuke Tanigawara ,  Tetsuya Suzuki ,  Akito Nishimuta ,  Shinji Sugimoto ,  Yoshiaki Igarashi

    发明人： Yusuke Tanigawara ,  Tetsuya Suzuki ,  Akito Nishimuta ,  Shinji Sugimoto ,  Yoshiaki Igarashi

    IPC分类号： A61K31/4375 ,  A61P35/00 ,  A61K31/4745 ,  G01N33/50 ,  G01N33/574 ,  G01N33/18

    CPC分类号： A61K31/4745 ,  G01N33/18 ,  G01N33/5011 ,  G01N33/574 ,  G01N33/6848 ,  G01N2500/00 ,  G01N2800/52

    摘要： To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker.The marker for determining sensitivity to an anti-cancer agent is formed of one or more substances selected from the group consisting of a substance or a fragment thereof detected as an anion at m/z of 149.05 to 149.06, a substance or a fragment thereof detected as an anion at m/z of 152.99 to 153.00, a substance or a fragment thereof detected as a cation at m/z of 724.34 to 724.35, the peaks being determined by means of a mass spectrometer, glycerol 3-phosphate, dihydrobiopterin, GABA, lactic acid, asparagine, aspartic acid, 2-methylbutyroylcarnitine, 1-methyladenosine, and glutathione, and a substance involved in a metabolic pathway of any of these substances.

    摘要翻译： 提供用于确定患者对抗癌剂的敏感性的标记物，以及采用该标记物的新型癌症治疗方法。 用于确定对抗癌剂的敏感性的标记物由选自以m / z为149.05至149.06作为阴离子检测的物质或其片段的一种或多种物质形成，检测到其物质或片段 作为m / z为152.99〜153.00的阴离子，以m / z为724.34〜724.35检测为阳离子的物质或其片段，通过质谱仪，甘油3-磷酸，二氢生物蝶呤，GABA ，乳酸，天冬酰胺，天冬氨酸，2-甲基丁酰基肉碱，1-甲基腺苷和谷胱甘肽，以及涉及任何这些物质的代谢途径的物质。

    Motor driving device and motor driving method
    4.
    发明授权
    Motor driving device and motor driving method 有权

    公开(公告)号：US07298106B2

    公开(公告)日：2007-11-20

    申请号：US11490985

    申请日：2006-07-21

    申请人： Yasunori Yamamoto ,  Hideaki Mori ,  Shinichi Kuroshima ,  Yoshiaki Igarashi

    发明人： Yasunori Yamamoto ,  Hideaki Mori ,  Shinichi Kuroshima ,  Yoshiaki Igarashi

    IPC分类号： H02P25/12

    CPC分类号： H02P6/182

    摘要： A rotor position sensorless multiphase motor driving device includes a rotor; a plurality of phase windings; a common terminal to which one terminal of terminals at both ends of each winding is star connected; an upper-side drive transistor and a lower-side drive transistor connected to the other terminal of the winding; a commutation control unit operable to select two terminals other than the common terminal of the windings, and to turn on the corresponding pair of upper-side drive transistor and the lower-side drive transistor; a rotor position search pulse applying unit operable to apply a search pulse to the selected two terminals; and a comparing unit operable to detect a rotor position based on a response signal generated between the terminal which was unselected and the common terminal according to the search pulse application.

    Reagent container
    5.
    发明申请
    Reagent container 审中-公开
    试剂容器

    公开(公告)号：US20050142040A1

    公开(公告)日：2005-06-30

    申请号：US11002084

    申请日：2004-12-03

    申请人： Masaaki Hanawa ,  Isao Yamazaki ,  Hitoshi Tokieda ,  Tomonori Mimura ,  Tadashi Oishi ,  Yoshiaki Igarashi ,  Masaharu Nishida ,  Takeshi Sato

    发明人： Masaaki Hanawa ,  Isao Yamazaki ,  Hitoshi Tokieda ,  Tomonori Mimura ,  Tadashi Oishi ,  Yoshiaki Igarashi ,  Masaharu Nishida ,  Takeshi Sato

    IPC分类号： G01N35/02 ,  B01L3/08 ,  B65D21/02 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10 ,  B01L3/00

    CPC分类号： G01N35/1002 ,  B01L3/08 ,  B01L2200/028 ,  B65D21/0202 ,  G01N2035/0443 ,  G01N2035/0451

    摘要： A reagent container used for automatic analysis in an automatic analyzer, which enables reagents to be set with ease and which can increase flexibility in selecting combinations of the reagents. In an automatic analyzer for analyzing components of a biological sample by using two or more kinds of reagents, reagent containers containing the two or more kinds of reagents are jointed into one reagent cassette with the aid of a recess and a projection provided in and on the reagent containers, a reagent holder, bonding, tape binding, etc. Thus, a plurality of reagents used for one analysis item are combined with each other in one cassette corresponding to one analysis item. A reagent container for use in automatic analysis, which is easy to handle and highly flexible in setting of reagents, can be provided.

    摘要翻译： 用于自动分析仪中的自动分析的试剂容器，其能够容易地设置试剂，并且可以增加选择试剂组合的灵活性。 在通过使用两种以上试剂分析生物样品的成分的自动分析装置中，含有两种或更多种试剂的试剂容器借助于凹部和凸起部分被连接在一个试剂盒中 试剂容器，试剂保持器，粘合，胶带结合等。因此，用于一个分析项目的多个试剂在与一个分析项目相对应的一个盒中彼此组合。 可以提供用于自动分析的试剂容器，其易于处理并且在设置试剂时具有高度灵活性。

    Motor control apparatus
    6.
    发明授权
    Motor control apparatus 有权
    电机控制装置

    公开(公告)号：US6081087A

    公开(公告)日：2000-06-27

    申请号：US178664

    申请日：1998-10-26

    申请人： Tomokuni Iijima ,  Kazushige Narazaki ,  Yoshiaki Igarashi ,  Taro Kishibe ,  Yukinori Maruyama

    发明人： Tomokuni Iijima ,  Kazushige Narazaki ,  Yoshiaki Igarashi ,  Taro Kishibe ,  Yukinori Maruyama

    IPC分类号： H02P21/14 ,  H02P6/14

    CPC分类号： H02P6/16 ,  G01D5/2449 ,  H02P21/18

    摘要： A motor controller according to the present invention is so configured that time interval measuring means measures the time interval of a rotational position signal indicating the rotational position of a rotor based on said rotational position signal, correction coefficient storage means stores the correction coefficient indicating the inaccuracy of said rotational position signal, estimated rotational angle production means produces an estimated rotational angle providing an estimated value of the rotational angle by extrapolating the rotational angle based on said time interval and said correction coefficient, and command production means produces a current command or a voltage command based on said estimated rotational angle and outputs it to driving means for driving a motor.

    摘要翻译： 根据本发明的电动机控制器被构造成使得时间间隔测量装置基于所述旋转位置信号来测量指示转子的旋转位置的旋转位置信号的时间间隔，校正系数存储装置存储指示不准确性的校正系数 所述旋转位置信号的估计旋转角产生装置根据所述时间间隔和所述校正系数，通过外推旋转角度产生提供旋转角度的估计值的估计旋转角度，并且指令产生装置产生电流指令或电压 命令，并将其输出到用于驱动马达的驱动装置。

    Controller for permanent magnet synchronous motor
    7.
    发明授权
    Controller for permanent magnet synchronous motor 失效
    永磁同步电机控制器

    公开(公告)号：US5652495A

    公开(公告)日：1997-07-29

    申请号：US445938

    申请日：1995-05-22

    申请人： Kazushige Narazaki ,  Tomokuni Iijima ,  Yoshiaki Igarashi ,  Satoshi Tamaki

    发明人： Kazushige Narazaki ,  Tomokuni Iijima ,  Yoshiaki Igarashi ,  Satoshi Tamaki

    IPC分类号： H02P1/46 ,  H02P21/00

    CPC分类号： H02P21/02 ,  H02P21/0089 ,  H02P21/06

    摘要： A controller for a permanent magnet synchronous motor which includes a D-axis current command section and a Q-axis current command section. The D-axis current command section increases the command value of the D-axis current so as to set a judged value to be zero by leading the current phase when the judged value is positive. In addition, the D-axis current command section decreases the command value of the D-axis current when the judged value is negative. Moreover, the D-axis current command section holds the command value of the D-axis current at a predetermined minimum value when the decreasing command value of the D-axis current becomes smaller than the predetermined minimum value. The Q-axis current command section is responsible for supplying a command value of the Q-axis current.

    摘要翻译： 一种用于永磁同步电动机的控制器，包括D轴电流指令部分和Q轴电流指令部分。 D轴电流指令部分增加D轴电流的指令值，以便当判断值为正时通过引导当前相位将判断值设置为零。 此外，当判断值为负时，D轴电流指令部分减小D轴电流的指令值。 此外，当D轴电流的减小指令值变得小于预定的最小值时，D轴电流指令部分将D轴电流的指令值保持在预定的最小值。 Q轴电流指令部分负责提供Q轴电流的指令值。

    Insulation-piercing connector
    9.
    发明授权
    Insulation-piercing connector 失效
    绝缘穿孔连接器

    公开(公告)号：US5417583A

    公开(公告)日：1995-05-23

    申请号：US250376

    申请日：1994-05-27

    申请人： Sadao Ishizaki ,  Yoshiaki Igarashi

    发明人： Sadao Ishizaki ,  Yoshiaki Igarashi

    IPC分类号： H01R4/24 ,  H01R13/58

    CPC分类号： H01R4/2433

    摘要： An insulation-piercing connector includes a terminal block having therein a plurality of piercing terminals, and a piercing block having wire receiving apertures. When the terminal and piercing blocks are forced closer together, insulated wires of a cable received in the wire receiving apertures of the piercing block are forced into U-shaped grooves of the piercing terminals so that inner edges of the U-shaped grooves pierce into conductors of the insulated wires to electrically connect between the conductors and the piercing terminals, respectively. The piercing block is further formed at the forward ends of the wire receiving apertures with U-shaped grooves whose opposed walls form flanges which may be tapered toward each other. A distance between the opposed walls of the U-shaped grooves is less than the outer diameter of the insulated wires but more than the outer diameter of the conductors of the wires.

    摘要翻译： 绝缘穿刺连接器包括其中具有多个穿孔端子的端子块和具有导线接收孔的穿孔块。 当端子和穿孔块被迫靠近在一起时，容纳在穿孔块的电线接收孔中的电缆的绝缘电线被迫入穿孔端子的U形槽中，使得U形槽的内边缘穿入导体 的绝缘电线分别电连接在导体和穿孔端子之间。 穿孔块进一步形成在具有U形槽的电线接收孔的前端处，其相对的壁形成可以朝向彼此逐渐变细的凸缘。 U形槽的相对壁之间的距离小于绝缘电线的外径，但大于电线导体的外径。