Placement of a marker is performed efficiently, when performing a plurality of radiation imaging operations of a subject with different imaging angles. An operator inputs a region of interest within a subject on a bed, via an operating section. The region of interest and a peripheral region thereof are set as an irradiation range, and the marker is placed in the peripheral region. A radiation source control section causes a radiation source to emit radiation toward the subject within the set irradiation range. Radiation which passes through the subject is obtained by a radiation image detector as a radiation image.