发明申请
US20100256168A1 QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
有权
喹诺酮类作为人类磷酸肌氨酸激酶3激酶抑制剂
- 专利标题： QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
- 专利标题（中）： 喹诺酮类作为人类磷酸肌氨酸激酶3激酶抑制剂
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申请号： US12732128申请日： 2010-03-25
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公开(公告)号： US20100256168A1公开(公告)日： 2010-10-07
- 发明人: Kerry W. Fowler , Danwen Huang , Edward A. Kesicki , Hua Chee Ooi , Amy Oliver , Fuqiang Ruan , Jennifer Treiberg
- 申请人： Kerry W. Fowler , Danwen Huang , Edward A. Kesicki , Hua Chee Ooi , Amy Oliver , Fuqiang Ruan , Jennifer Treiberg
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; A61P35/02 ; A61P35/00
摘要：
Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed.
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