发明申请
US20100256213A1 Tosylate Salt Of Trans-N-Isobutyl-3-Fluoro-3- [3-Fluoro-4-(Pyrrolidin-1-YL-Methyl)-Phenyl] Cyclobut Anecarboxamide 失效
反式异丁基-3-氟-3- [3-氟-4-(吡咯烷-1-基 - 甲基) - 苯基]环丁烷甲酰胺的甲苯磺酸盐

Tosylate Salt Of Trans-N-Isobutyl-3-Fluoro-3- [3-Fluoro-4-(Pyrrolidin-1-YL-Methyl)-Phenyl] Cyclobut Anecarboxamide
摘要:
The present invention is directed to the tosylate salt of trans-N-isobutyl-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)-phenyl]-cyclobutanecarboxamide Formula (I): to solvates (e.g., hydrates) thereof, to polymorphs thereof, to pharmaceutical compositions thereof and to a method of treating depression, mood disorders, schizophrenia, anxiety disorders, cognitive disorders, Alzheimer's disease, attention-deficit disorder (ADD), attention-deficit hyperactivity disorder (ADHD), psychotic disorders, sleep disorders, obesity, dizziness, epilepsy, motion sickness, respiratory diseases, allergy, allergy-induced airway responses, allergic rhinitis, nasal congestion, allergic congestion, congestion, hypotension, cardiovascular disease, diseases of the GI tract, hyper- and hypo-motility and acidic secretion of the gastro-intestinal tract comprising administering a therapeutically effective amount thereof.
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