发明申请
US20100267725A1 Compounds, Compositions and Methods Comprising 4N-Substituted Triazole Derivatives
审中-公开
包含4N取代的三唑衍生物的化合物，组合物和方法
- 专利标题： Compounds, Compositions and Methods Comprising 4N-Substituted Triazole Derivatives
- 专利标题（中）： 包含4N取代的三唑衍生物的化合物，组合物和方法
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申请号： US12763831申请日： 2010-04-20
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公开(公告)号： US20100267725A1公开(公告)日： 2010-10-21
- 发明人: Michael Geoffrey Neil Russell , Kevin James Doyle
- 申请人： Michael Geoffrey Neil Russell , Kevin James Doyle
- 专利权人： Institute for OneWorld Health
- 当前专利权人： Institute for OneWorld Health
- 主分类号： A61K31/4196
- IPC分类号： A61K31/4196 ; C07D249/10 ; C07D401/06 ; A61K31/4439 ; C07D401/04 ; C07D413/10 ; A61K31/5377 ; A61P29/00 ; A61P1/12 ; A61P1/00 ; A61P9/06 ; A61P13/12 ; A61P15/10 ; C12N5/02
摘要：
The present invention relates to compounds, compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Table 1 or 2 or encompassed by formula I) or compositions comprising these compounds, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
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