发明申请
US20100267983A1 WATER-SOLUBLE TRITERPENEPHENOL COMPOUNDS HAVING ANTITUMOR ACTIVITY AND THE PREPARATION THEREOF
有权
具有抗肿瘤活性的水溶性三羟甲基苯酚化合物及其制备方法
- 专利标题： WATER-SOLUBLE TRITERPENEPHENOL COMPOUNDS HAVING ANTITUMOR ACTIVITY AND THE PREPARATION THEREOF
- 专利标题（中）： 具有抗肿瘤活性的水溶性三羟甲基苯酚化合物及其制备方法
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申请号： US12743101申请日： 2008-11-05
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公开(公告)号： US20100267983A1公开(公告)日： 2010-10-21
- 发明人: Jiafeng Zeng , Junfang Pan , Baoying Li , Qin Zhu , Tong Fang , Huiyan Ni
- 申请人： Jiafeng Zeng , Junfang Pan , Baoying Li , Qin Zhu , Tong Fang , Huiyan Ni
- 申请人地址： CN Shanghai
- 专利权人： SHANGHAI HUATUO MEDICAL SCIENCE CO., LTD
- 当前专利权人： SHANGHAI HUATUO MEDICAL SCIENCE CO., LTD
- 当前专利权人地址： CN Shanghai
- 优先权： CN200710170537.2 20071116
- 国际申请： PCT/CN2008/072959 WO 20081105
- 主分类号： C07C309/60
- IPC分类号： C07C309/60 ; C07C69/753
摘要：
The invention discloses water-soluble triterpenephenol compounds having antitumor activity represented by formula (I), wherein the substituents R1˜R4 and M are defined as in the description. The invention also discloses a method for preparing the compounds of formula (I) used quinone methide triterpene compounds as starting materials. The water-soluble triterpenephenol compounds disclosed in the invention can be made into various dosage forms including injection, tablet, capsule, granule and liniment, particularly suitable for making into injection.
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