发明申请
US20100279325A1 USE OF MODIFIED EXTRACELLULAR MATRIX PROTEINS IN DIAGNOSIS AND TREATMENT OF ATHEROSCLEROSIS
审中-公开
改良的细胞外基质蛋白在诊断和治疗角质层病中的应用
- 专利标题： USE OF MODIFIED EXTRACELLULAR MATRIX PROTEINS IN DIAGNOSIS AND TREATMENT OF ATHEROSCLEROSIS
- 专利标题（中）： 改良的细胞外基质蛋白在诊断和治疗角质层病中的应用
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申请号： US12814137申请日： 2010-06-11
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公开(公告)号： US20100279325A1公开(公告)日： 2010-11-04
- 发明人: Jan Nilsson
- 申请人： Jan Nilsson
- 申请人地址： SE Lund
- 专利权人： FORSKARPATENT I SYD AB
- 当前专利权人： FORSKARPATENT I SYD AB
- 当前专利权人地址： SE Lund
- 优先权： SE0400683-9 20040319
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07K16/00
摘要：
The present invention relates to the use of fibronectin, tenascin, collagens type I, III, VI and/or VIII modified by aldehyde or by glycosylation in ELISA for detection of antibodies in plasma and serum to diagnose atherosclerosis as well as the use of induction of tolerance and active as well as passive immunization against glycosylated or aldehydemodified fibronectin, tenascin, collagen type I, III, VI and/or VIII for prevention and treatment of atherosclerosis.
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