Invention Application
- Patent Title: POLYPEPTIDE INHIBITING TRANSMIGRATION OF LEUKOCYTES OR GROWTH AND/OR METASTASIS OF CANCER CELLS, AND FUSION PROTEIN THEREOF
- Patent Title (中): 多肽抑制寡核苷酸的转移或癌细胞的增殖和/或转移及其融合蛋白
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Application No.: US11991310Application Date: 2006-09-20
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Publication No.: US20100286064A1Publication Date: 2010-11-11
- Inventor: Jang-Hee Hahn , Kyoung-Jin Lee , Dong-Min Kang
- Applicant: Jang-Hee Hahn , Kyoung-Jin Lee , Dong-Min Kang
- Priority: KR10-2005-0090668 20050928; KR10-2006-0060890 20060630; KR10-2006-0067440 20060719
- International Application: PCT/KR2006/003728 WO 20060920
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K5/10 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; C07H21/04 ; C12N15/63 ; C12N1/21 ; C12N1/19 ; A61K38/07 ; A61K38/08 ; A61K38/10 ; A61P29/00 ; A61P35/00
Abstract:
The present invention provides a polypeptide inhibiting the transmigration of leukocytes or the growth and/or metastasis of cancer cells, or a fusion protein thereof. The present invention also provides a polynucleotide encoding the polypeptide, a vector including the polynucleotide, and a transformant transformed with the vector. The present invention also provides a pharmaceutical composition for the prevention or treatment of inflammatory diseases including the polypeptide or a fusion protein thereof. The present invention also provides a pharmaceutical composition for inhibiting the growth and/or metastasis of cancer cells including the polypeptide or a fusion protein thereof.
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