发明申请
US20100286374A1 METHOD FOR MAKING ANTIBODY FC-HETERODIMERIC MOLECULES USING ELECTROSTATIC STEERING EFFECTS
有权
使用静电转向效应制备抗体FC-高分子量分子的方法
- 专利标题: METHOD FOR MAKING ANTIBODY FC-HETERODIMERIC MOLECULES USING ELECTROSTATIC STEERING EFFECTS
- 专利标题(中): 使用静电转向效应制备抗体FC-高分子量分子的方法
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申请号: US12811207申请日: 2009-01-06
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公开(公告)号: US20100286374A1公开(公告)日: 2010-11-11
- 发明人: Gunasekaran Kannan , Michael Wittekind , Wei Yan , Martin Pentony
- 申请人: Gunasekaran Kannan , Michael Wittekind , Wei Yan , Martin Pentony
- 国际申请: PCT/US09/00071 WO 20090106
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C12P21/06 ; C12N5/10 ; C12N15/63 ; C07H21/04
摘要:
The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer. Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to pharmaceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.
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