- 专利标题： ALIPHATIC PRODRUG LINKER
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申请号： US11993645申请日： 2006-06-21
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公开(公告)号： US20100291021A1公开(公告)日： 2010-11-18
- 发明人: Dirk Vetter , Harald Rau , Thomas Wegge
- 申请人： Dirk Vetter , Harald Rau , Thomas Wegge
- 优先权： GB0512705.5 20050622
- 国际申请： PCT/EP2006/063418 WO 20060621
- 主分类号： A61K31/787
- IPC分类号： A61K31/787 ; A61P25/00 ; A61P31/00 ; A61P35/00 ; A61P31/04 ; A61P31/10 ; A61P29/00 ; A61P9/08 ; A61P9/00 ; C08G63/91 ; A61K31/765
摘要：
A polymeric prodrug is described which comprises at least one polymer attached via at least one permanent bond to a bicine linker. The bicine linker is attached via a temporary linkage to an amine containing biologically active moiety. The amine containing biologically active moiety—such as a drug—can be released by cleaving the temporary linkage.
公开/授权文献
- US08980242B2 Aliphatic prodrug linker 公开/授权日：2015-03-17
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