发明申请
- 专利标题： METHODS AND COMPOSITIONS FOR ANTIBODY THERAPY
- 专利标题（中）： 抗体治疗方法和组合物
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申请号： US12298661申请日： 2007-04-27
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公开(公告)号： US20100291549A1公开(公告)日： 2010-11-18
- 发明人: Vijay Ramakrishnan
- 申请人： Vijay Ramakrishnan
- 申请人地址： US CA Menlo Park
- 专利权人： PIKAMAB, INC.
- 当前专利权人： PIKAMAB, INC.
- 当前专利权人地址： US CA Menlo Park
- 国际申请： PCT/US07/67663 WO 20070427
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Methods and materials are provided for determining the responsiveness of a subject to a therapy, such as an antibody therapy and for selecting and/or for treating a subject based on a FcγRIIA polymorphism, or a FcγRIIIA polymorphism, or both an FcγRIIA polymorphism and a FcγRIIIA polymorphism, including where the treatment is an therapy, such as rituximab. Methods and materials are also provided for designing, making, screening, testing and/or administering antibodies as well as for optimizing antibody therapies based upon a subject's FcγRIIA polymorphism, or FcγRIIIA polymorphism, or both the FcγRIIA polymorphism and the FcγRIIIA polymorphism.
公开/授权文献
- US08592149B2 Methods and compositions for antibody therapy 公开/授权日：2013-11-26
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