发明申请
- 专利标题： SUSTAINED-RELEASE PHARMACEUTICAL FORMULATION CONTAINING AN ANTIMUSCARINIC AGENT AND A WETTING AGENT AS WELL AS A PROCESS FOR THE PREPARATION THEREOF
- 专利标题（中）： 包含抗细菌剂和湿润剂的持续释放药物制剂作为其制备方法
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申请号： US12747211申请日： 2007-12-20
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公开(公告)号： US20100297225A1公开(公告)日： 2010-11-25
- 发明人: Evangelos Karavas , Efthimios Koutris , Ioanna Koutri , Vicky Samara , Dimitrios Bikiaris
- 申请人： Evangelos Karavas , Efthimios Koutris , Ioanna Koutri , Vicky Samara , Dimitrios Bikiaris
- 申请人地址： GR PALLINI-ATTIKIS
- 专利权人： PHARMATHEN S.A.
- 当前专利权人： PHARMATHEN S.A.
- 当前专利权人地址： GR PALLINI-ATTIKIS
- 国际申请： PCT/EP2007/011230 WO 20071220
- 主分类号： A61K9/52
- IPC分类号： A61K9/52 ; A61K31/137 ; A61P13/00
摘要：
The present invention relates to improved sustained release dosage forms such as tablets and capsules, and in particular to a pharmaceutical formulation for oral administration comprising a therapeutically effective quantity of an antimuscarinic agent, such as Tolterodine or pharmaceutical acceptable salt, derivative, prodrug and metabolite thereof in combination with a wetting agent, such as Sodium Docusate to improve the release of the active ingredient and a method for the preparation thereof.
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