发明申请
- 专利标题： ANTAGONISTS OF PGD2 RECEPTORS
- 专利标题（中）： PGD2受体拮抗剂
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申请号： US12741805申请日： 2008-10-31
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公开(公告)号： US20100298368A1公开(公告)日： 2010-11-25
- 发明人: Brian Andrew Stearns , John Howard Hutchinson
- 申请人： Brian Andrew Stearns , John Howard Hutchinson
- 申请人地址： US CA San DIego
- 专利权人： AMIRA PHARMACEUTICALS, INC.
- 当前专利权人： AMIRA PHARMACEUTICALS, INC.
- 当前专利权人地址： US CA San DIego
- 国际申请： PCT/US08/82082 WO 20081031
- 主分类号： A61K31/438
- IPC分类号： A61K31/438 ; C07D295/027 ; C07D295/26 ; A61P11/06 ; A61P29/00 ; A61P9/12 ; A61P19/02 ; A61P17/06 ; A61P35/00 ; A61P11/14 ; A61P9/00 ; A61P37/08 ; A61P11/00 ; A61P9/10
摘要：
Described herein are compounds and pharmaceutical compositions containing such compounds that modulate the PGD2 activated chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2). Also described herein are methods of using such CRTH2 modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2 mediated conditions or diseases.
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