发明申请
US20100311671A1 TRANSDERMAL DELIVERY OF PKC MODULATORY PEPTIDES THROUGH MICROPORATED SKIN
审中-公开
通过微孔皮肤转移PKC调节性胶原蛋白
- 专利标题： TRANSDERMAL DELIVERY OF PKC MODULATORY PEPTIDES THROUGH MICROPORATED SKIN
- 专利标题（中）： 通过微孔皮肤转移PKC调节性胶原蛋白
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申请号： US12732091申请日： 2010-03-25
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公开(公告)号： US20100311671A1公开(公告)日： 2010-12-09
- 发明人: Randolph Mellus Johnson , Felix Karim , Lisa Christine Ryner
- 申请人： Randolph Mellus Johnson , Felix Karim , Lisa Christine Ryner
- 申请人地址： US CA South San Francisco
- 专利权人： Kai Pharmaceuticals
- 当前专利权人： Kai Pharmaceuticals
- 当前专利权人地址： US CA South San Francisco
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; A61K38/02 ; A61K38/10 ; A61K38/08
摘要：
Disclosed herein are methods for transdermal delivery of PKC modulatory peptides. Generally, methods comprise the delivery of an isozyme specific PKC peptide modulator through skin that has been microporated, e.g., with an array of microneedles. Such methods may be used to administer therapeutically effective amounts of an isozyme selective PKC peptide inhibitor or activator.
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