发明申请
- 专利标题： LABELING OF HUMAN EPIDERMAL STEM CELLS
- 专利标题（中）： 人类干细胞标记物
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申请号： US12446364申请日： 2007-10-29
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公开(公告)号： US20100323384A1公开(公告)日： 2010-12-23
- 发明人: Hans-Jürgen Stark , Sonja Muffler , Mara Amoros-Alonso , Norbert Fusenig , Petra Boukamp
- 申请人： Hans-Jürgen Stark , Sonja Muffler , Mara Amoros-Alonso , Norbert Fusenig , Petra Boukamp
- 申请人地址： DE Heidelberg DE Stuttgart
- 专利权人： Deutsches Krebsforschungszentrum Stiftung des oeffentlichen Rechtass,Landesstiftung Baden-Wuerttemberg gGmbH
- 当前专利权人： Deutsches Krebsforschungszentrum Stiftung des oeffentlichen Rechtass,Landesstiftung Baden-Wuerttemberg gGmbH
- 当前专利权人地址： DE Heidelberg DE Stuttgart
- 优先权： EP06123181.7 20061030
- 国际申请： PCT/EP2007/061610 WO 20071029
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; C12N5/074
摘要：
The present invention provides skin equivalents comprising human epidermal stem cells which are specifically labeled. The labeling is carried out with a marker capable of labeling slowly proliferating cells, e.g. iododeoxyuridine or PKH26. Particularly, the invention provides skin equivalents comprising labeled epidermal stem cells. The invention also provides corresponding uses and methods of using such cultures, e.g. in the fields of research and medical treatment of skin diseases.
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