Techniques are disclosed for asynchronous calibration for eye diagram generation. For example, a method for calibrating a process for generating a data eye associated with a received signal comprises the following steps. Samples of the received signal are obtained for a first unit interval using a first data latch and a roaming latch. A delay offset is determined between the first data latch and the roaming latch by comparing at least one sample obtained using the first data latch and at least one sample obtained using the roaming latch, wherein the delay offset determined by the comparison is used to calibrate the process for generating the data eye associated with the received signal. A similar comparison may be done for a second data latch and used to calibrate the process. The method is able to find the accurate position of each data latch with respect to the roaming latch so as to improve the accuracy of data decoding in a digital receiver, i.e., provide receiver optimization.