Invention Application
- Patent Title: MODULATORS OF LXR
- Patent Title (中): LXR调制器
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Application No.: US11993806Application Date: 2006-06-26
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Publication No.: US20100331295A1Publication Date: 2010-12-30
- Inventor: Brett B Busch , Brenton T. Flatt , Xiao Hui Gu , Shao Po Lu , Richard Martin , Raju Mohan , Michael Charles Nyman , Edwin Schweiger , William C. Stevens, JR. , Tie Lin Wang , Yinong Xie
- Applicant: Brett B Busch , Brenton T. Flatt , Xiao Hui Gu , Shao Po Lu , Richard Martin , Raju Mohan , Michael Charles Nyman , Edwin Schweiger , William C. Stevens, JR. , Tie Lin Wang , Yinong Xie
- Applicant Address: US CA South San Francisco
- Assignee: EXELIXIS, INC.
- Current Assignee: EXELIXIS, INC.
- Current Assignee Address: US CA South San Francisco
- International Application: PCT/US06/24749 WO 20060626
- Main IPC: A61K31/4155
- IPC: A61K31/4155 ; C07D409/04 ; C07D231/12 ; C07D401/04 ; C07D413/10 ; C07D409/14 ; C07D403/10 ; A61K31/4439 ; A61K31/454 ; A61K31/5377 ; A61K31/496 ; A61P3/06 ; A61P3/10 ; A61P9/10 ; A61P17/10 ; A61P25/16 ; A61P25/28 ; A61P35/00 ; A61P29/00 ; A61P37/00 ; A61P3/04
Abstract:
Compounds of the invention, such as compounds of Formulae Ia, Ib, Ic, or Id and pharmaceutically acceptable salts, isomers, and prodrugs thereof, which are useful as modulators of the activity of liver X receptors, where R1, R2, R21, R3, and G are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
Public/Granted literature
- US08703805B2 Modulators of LXR Public/Granted day:2014-04-22
Information query
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