发明申请
- 专利标题： MODULATORS OF LXR
- 专利标题（中）： LXR调制器
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申请号： US11993806申请日： 2006-06-26
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公开(公告)号： US20100331295A1公开(公告)日： 2010-12-30
- 发明人: Brett B Busch , Brenton T. Flatt , Xiao Hui Gu , Shao Po Lu , Richard Martin , Raju Mohan , Michael Charles Nyman , Edwin Schweiger , William C. Stevens, JR. , Tie Lin Wang , Yinong Xie
- 申请人： Brett B Busch , Brenton T. Flatt , Xiao Hui Gu , Shao Po Lu , Richard Martin , Raju Mohan , Michael Charles Nyman , Edwin Schweiger , William C. Stevens, JR. , Tie Lin Wang , Yinong Xie
- 申请人地址： US CA South San Francisco
- 专利权人： EXELIXIS, INC.
- 当前专利权人： EXELIXIS, INC.
- 当前专利权人地址： US CA South San Francisco
- 国际申请： PCT/US06/24749 WO 20060626
- 主分类号： A61K31/4155
- IPC分类号： A61K31/4155 ; C07D409/04 ; C07D231/12 ; C07D401/04 ; C07D413/10 ; C07D409/14 ; C07D403/10 ; A61K31/4439 ; A61K31/454 ; A61K31/5377 ; A61K31/496 ; A61P3/06 ; A61P3/10 ; A61P9/10 ; A61P17/10 ; A61P25/16 ; A61P25/28 ; A61P35/00 ; A61P29/00 ; A61P37/00 ; A61P3/04
摘要：
Compounds of the invention, such as compounds of Formulae Ia, Ib, Ic, or Id and pharmaceutically acceptable salts, isomers, and prodrugs thereof, which are useful as modulators of the activity of liver X receptors, where R1, R2, R21, R3, and G are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.
公开/授权文献
- US08703805B2 Modulators of LXR 公开/授权日：2014-04-22
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