Invention Application
- Patent Title: AZATRICYCLIC ANTIBIOTIC COMPOUNDS
- Patent Title (中): 亚胺基抗生素化合物
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Application No.: US12918749Application Date: 2009-02-19
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Publication No.: US20100331318A1Publication Date: 2010-12-30
- Inventor: Christian Hubschwerlen , Georg Rueedi , John-Philippe Surivet , Cornelia Zumbrunn-Acklin
- Applicant: Christian Hubschwerlen , Georg Rueedi , John-Philippe Surivet , Cornelia Zumbrunn-Acklin
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee Address: CH Allschwil
- Priority: IBPCT/IB2008/050603 20080220; IBPCT/IB2008/054065 20081003
- International Application: PCT/IB09/50675 WO 20090219
- Main IPC: A61K31/5415
- IPC: A61K31/5415 ; C07D413/14 ; C07D471/06 ; A61K31/538 ; A61K31/4375 ; A61P31/04

Abstract:
The invention relates to antibacterial compounds of formula I wherein n is 0 or 1; R1 represents H or F; U represents CH2 or, provided n is 1, O or NH; “-----” is a bond or is absent; V represents CH or N when “-----” is a bond, or CH2 or NH when “-----” is absent; W represents CH or N; A represents —(CH—)p—NH—(CH2)q— wherein p is 1 and q is 1 or 2 or, provided U represents CH2 and n is 1, p may also be 0 and q is then 2; G represents one of the groups wherein Z represents N or CH and Q represents O or S; and Z0, Z1 and Z2 each represent CH, or Z0 and Z1 each represent CH and Z2 represents N, or Z0 represents CH, Z1 represents N and Z2 represents CH or N, or Z0 represents N and Z1 and Z2 each represent CH; and to salts of such compounds.
Public/Granted literature
- US08349828B2 Azatricyclic antibiotic compounds Public/Granted day:2013-01-08
Information query
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