发明申请
- 专利标题： INHIBITORS OF JAK
- 专利标题（中）： JAK的抑制剂
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申请号： US12775358申请日： 2010-05-06
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公开(公告)号： US20110005947A1公开(公告)日： 2011-01-13
- 发明人: Shawn M. Bauer , Jack W. Rose , Yonghong Song , Qing Xu , Mukund Mehrotra , Wolin Huang , Anjali Pandey
- 申请人： Shawn M. Bauer , Jack W. Rose , Yonghong Song , Qing Xu , Mukund Mehrotra , Wolin Huang , Anjali Pandey
- 申请人地址： US CA South San Francisco
- 专利权人： Portola Pharmaceuticals, Inc.
- 当前专利权人： Portola Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： B65D85/00
- IPC分类号： B65D85/00 ; C07D239/48 ; A61K31/505 ; C07D403/12 ; A61K31/506 ; C07D405/12 ; C07D413/12 ; A61K31/5377 ; C07D403/14 ; C07D401/12 ; C07D417/12 ; C07D401/14 ; A61K31/444 ; A61K31/4427 ; A61K31/4439 ; A61P29/00 ; A61P3/10 ; A61P25/00 ; A61P37/06 ; A61P9/00 ; A61P11/06
摘要：
The present invention is directed to compounds of formula I and tautomers and pharmaceutically acceptable salts thereof which are selective inhibitors of JAK. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK activity, and methods to prevent or treat a number of conditions mediated at least in part by JAK activity.
公开/授权文献
- US08367689B2 Inhibitors of JAK 公开/授权日：2013-02-05
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