发明申请
US20110009589A1 DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM
审中-公开
可降解的异戊二烯（乙二醇）丙烯酸酯和凝胶以及其衍生物
- 专利标题： DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM
- 专利标题（中）： 可降解的异戊二烯（乙二醇）丙烯酸酯和凝胶以及其衍生物
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申请号： US12860525申请日： 2010-08-20
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公开(公告)号： US20110009589A1公开(公告)日： 2011-01-13
- 发明人: J. Milton Harris , Xuan Zhao
- 申请人： J. Milton Harris , Xuan Zhao
- 申请人地址： US AL Huntsville
- 专利权人： Nektar Therapeutics AL., Corporation
- 当前专利权人： Nektar Therapeutics AL., Corporation
- 当前专利权人地址： US AL Huntsville
- 主分类号： C08F20/58
- IPC分类号： C08F20/58 ; C08F22/20
摘要：
A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coupling to a target. Hydrogels can be prepared. The hydrogels can be used as a carrier for a protein or a pharmaceutical agent that can be readily released in a controlled fashion.
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