发明申请
- 专利标题: PYRROLOPYRAZINE INHIBITORS OF KINASES
- 专利标题(中): 辣椒碱的吡咯啉抑制剂
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申请号: US12836637申请日: 2010-07-15
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公开(公告)号: US20110015172A1公开(公告)日: 2011-01-20
- 发明人: Thomas D. Penning , Virajkumar B. Gandhi , Gui-Dong Zhu , Yunsong Tong , Keith W. Woods , Chunqiu Lai , Jane Gong , Alan S. Florjancic
- 申请人: Thomas D. Penning , Virajkumar B. Gandhi , Gui-Dong Zhu , Yunsong Tong , Keith W. Woods , Chunqiu Lai , Jane Gong , Alan S. Florjancic
- 申请人地址: US IL Abbott Park
- 专利权人: ABBOTT LABORATORIES
- 当前专利权人: ABBOTT LABORATORIES
- 当前专利权人地址: US IL Abbott Park
- 主分类号: A61K31/4985
- IPC分类号: A61K31/4985 ; C07D471/04 ; A61P35/00
摘要:
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
公开/授权文献
- US08383624B2 Pyrrolopyrazine inhibitors of kinases 公开/授权日:2013-02-26