发明申请
US20110015218A1 AZA-BICYCLOHEXYL SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
有权
AZA-BICYCLOHEXYL取代的吲哚基氨基酸衍生物作为HISTONE DEACETYLASE的新型抑制剂
- 专利标题： AZA-BICYCLOHEXYL SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE
- 专利标题（中）： AZA-BICYCLOHEXYL取代的吲哚基氨基酸衍生物作为HISTONE DEACETYLASE的新型抑制剂
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申请号： US12934894申请日： 2009-03-26
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公开(公告)号： US20110015218A1公开(公告)日： 2011-01-20
- 发明人: Eddy Jean Edgard Freyne , Isabelle Noëlle Constance Pilatte , Patrick René Angibaud
- 申请人： Eddy Jean Edgard Freyne , Isabelle Noëlle Constance Pilatte , Patrick René Angibaud
- 申请人地址： BE Beerse
- 专利权人： JANSSEN PHARMACEUTICA NV
- 当前专利权人： JANSSEN PHARMACEUTICA NV
- 当前专利权人地址： BE Beerse
- 优先权： EP08153370.5 20080327
- 国际申请： PCT/EP2009/053566 WO 20090326
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D403/14 ; A61P35/00
摘要：
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4, A and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
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