- 专利标题： ARYL SULFONAMIDES
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申请号： US12896114申请日： 2010-10-01
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公开(公告)号： US20110021523A1公开(公告)日： 2011-01-27
- 发明人: Solomon Ugashe , Zheng Wei , J.J. Wright , Andrew Pennell
- 申请人： Solomon Ugashe , Zheng Wei , J.J. Wright , Andrew Pennell
- 申请人地址： US CA Mountain View
- 专利权人： CHEMOCENTRYX, INC.
- 当前专利权人： CHEMOCENTRYX, INC.
- 当前专利权人地址： US CA Mountain View
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; C07D413/12 ; C07D213/50 ; C07D239/26 ; C07D413/04 ; C07D213/70 ; C07D241/12 ; C07D213/84 ; A61K31/4409 ; A61K31/505 ; A61K31/5377 ; A61K31/44 ; A61K31/4965 ; A61P29/00 ; A61P37/00 ; A61P1/00 ; A61P37/08 ; A61P37/06 ; A61P17/06 ; A61P11/06 ; A61P17/00 ; A61P19/02 ; A61P35/00 ; A61P35/02
摘要：
Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
公开/授权文献
- US08211896B2 Aryl sulfonamides 公开/授权日：2012-07-03
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