发明申请
- 专利标题: QUATERNARY AMMONIUM DIPHENYLMETHYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS
- 专利标题(中): 季戊四醇二甲苯化合物可用作肌酐受体拮抗剂
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申请号: US12898861申请日: 2010-10-06
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公开(公告)号: US20110021787A1公开(公告)日: 2011-01-27
- 发明人: YuHua JI , Craig HUSFELD , Christopher LANGE , Rick LEE , YongQi MU
- 申请人: YuHua JI , Craig HUSFELD , Christopher LANGE , Rick LEE , YongQi MU
- 申请人地址: US CA South San Francisco
- 专利权人: THERAVANCE, INC.
- 当前专利权人: THERAVANCE, INC.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07D207/09
- IPC分类号: C07D207/09
摘要:
The invention provides compounds of formula I: in salt or zwitterionic form or a pharmaceutically acceptable salt thereof, wherein R1-6, a-e and Q are as defined in the specification. These compounds are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes for preparing such compounds and methods of using such compounds to, for example, treat pulmonary disorders such as chronic obstructive pulmonary disease and asthma.
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