发明申请
- 专利标题： Quantitation Method Using Isotope Labeled Internal Standard Substance, Analysis System for Executing the Quantitation Method, and Program for the Analysis
- 专利标题（中）： 使用同位素标记的内标物质的定量方法，执行定量方法的分析系统和分析程序
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申请号： US12787712申请日： 2010-05-26
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公开(公告)号： US20110022326A1公开(公告)日： 2011-01-27
- 发明人: Yoshiya ODA , Yasushi Ishihama , Tsuyoshi Tabata
- 申请人： Yoshiya ODA , Yasushi Ishihama , Tsuyoshi Tabata
- 专利权人： Eisai R&B Managament Co., Ltd.
- 当前专利权人： Eisai R&B Managament Co., Ltd.
- 优先权： JP2003-392690 20031121; JP2004-109845 20040402
- 主分类号： G06F19/00
- IPC分类号： G06F19/00 ; C12N5/07 ; C12Q1/02 ; C07C229/08
摘要：
Problem: An object of the present invention is to quantitate with good accuracy, furthermore, quantitate absolutely, one or a plurality of biological molecules in a sample such as a tissue, a biological fluid, a cell, a cell organ or protein complex.Solution: By adding a metabolically isotope labeled biological molecule as an internal standard substance and measuring with a mass spectrometer, quantitating with good accuracy one or a plurality of target molecules in a sample has become possible. In addition, by performing waveform separation processing during mass analysis, a highly accurate quantitative analysis method of mass analysis is provided.
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