发明申请
US20110027264A1 GAMMA SECRETASE MODULATORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
审中-公开
用于治疗阿尔茨海默病的GAMMA分泌调节剂
- 专利标题: GAMMA SECRETASE MODULATORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
- 专利标题(中): 用于治疗阿尔茨海默病的GAMMA分泌调节剂
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申请号: US12919574申请日: 2009-02-26
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公开(公告)号: US20110027264A1公开(公告)日: 2011-02-03
- 发明人: Xianhai Huang , Xianghai Huang , Anandan Palani , Robert G. Aslanian , Zhaoning Zhu , Dmitri A. Pissarnitski , Hongmei Li , William J. Greenlee , Zhiqiang Zhao , Robert D. Mazzola, JR. , Jun Qin , Pawan Dhondi
- 申请人: Xianhai Huang , Xianghai Huang , Anandan Palani , Robert G. Aslanian , Zhaoning Zhu , Dmitri A. Pissarnitski , Hongmei Li , William J. Greenlee , Zhiqiang Zhao , Robert D. Mazzola, JR. , Jun Qin , Pawan Dhondi
- 国际申请: PCT/US09/35266 WO 20090226
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07D401/12 ; C07D221/20 ; A61K38/16 ; A61K31/454 ; A61K31/438 ; A61P25/28
摘要:
This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula: Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).
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