发明申请
- 专利标题: INTERFERON ANTAGONISTS, ANTIBODIES THERETO AND ASSOCIATED METHODS OF USE
- 专利标题(中): 干扰素拮抗剂,抗体及其相关方法
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申请号: US12310432申请日: 2007-08-23
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公开(公告)号: US20110027282A1公开(公告)日: 2011-02-03
- 发明人: Sergei V. Kotenko , Geoffrey L. Smith
- 申请人: Sergei V. Kotenko , Geoffrey L. Smith
- 国际申请: PCT/US07/76655 WO 20070823
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K38/16 ; C07H21/00 ; C07K14/065 ; C12N15/63 ; C12N5/10 ; C12N1/00 ; C07K16/10 ; C40B30/04 ; C07H21/02 ; A61P37/02 ; A61P37/06 ; A61P31/12 ; A61P31/00
摘要:
Described are compositions and methods useful for modulating the immune system of a subject. Also included are diagnostic methods for monitoring an immunologic condition. In particular the invention relates to antagonists of interferon proteins and associated methods of use as well as methods to develop neutralizing antibodies against IFN antagonists to treat viral infections.
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