发明申请
- 专利标题： HYBRIDIZATION DEVICE, METHODS, AND SYSTEM USING MIXING BEADS
- 专利标题（中）： 混合装置，方法和使用混合珠的系统
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申请号： US12847570申请日： 2010-07-30
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公开(公告)号： US20110028352A1公开(公告)日： 2011-02-03
- 发明人: Bell Laurent , Martin J. Goldberg , Robert J. Lipshutz , Kaliyur Narasimhan
- 申请人： Bell Laurent , Martin J. Goldberg , Robert J. Lipshutz , Kaliyur Narasimhan
- 申请人地址： US CA Santa Clara
- 专利权人： Affymetrix, INC.
- 当前专利权人： Affymetrix, INC.
- 当前专利权人地址： US CA Santa Clara
- 主分类号： C40B50/18
- IPC分类号： C40B50/18 ; C40B60/14
摘要：
A method, device and system for hybridizing a target oligonucleotide to at least one array comprising a plurality of mixing beads are provided. A target solution is mixed by agitating the mixing beads while the target oligonucleotides are hybridizing to the complementary probes on the array. In another embodiment, a permeable barrier contains the mixing beads, thereby preventing them from contacting the array surface.
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