发明申请
US20110028466A1 NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES
有权
NITROIMIDAZOOXAZINE和NITROIMIDAZOOXAZOLE ANALOGUES及其用途
- 专利标题: NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES
- 专利标题(中): NITROIMIDAZOOXAZINE和NITROIMIDAZOOXAZOLE ANALOGUES及其用途
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申请号: US12847459申请日: 2010-07-30
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公开(公告)号: US20110028466A1公开(公告)日: 2011-02-03
- 发明人: Andrew Mark Thompson , William Alexander Denny , Adrian Blaser , Zhenkun Ma
- 申请人: Andrew Mark Thompson , William Alexander Denny , Adrian Blaser , Zhenkun Ma
- 申请人地址: US NY New York
- 专利权人: Global Alliance for TB Drug Development
- 当前专利权人: Global Alliance for TB Drug Development
- 当前专利权人地址: US NY New York
- 主分类号: A61K31/5365
- IPC分类号: A61K31/5365 ; A61K31/4965 ; A61K31/506 ; A61K31/4439 ; A61K31/424 ; C07D498/04 ; A61P31/04
摘要:
The current invention pertains to nitroimidazooxazine and nitroimidazooxazole analogues, their methods of preparation, and uses of the compounds as treatment for Mycobacterium tuberculosis, for use as anti-tubercular drugs, for use as anti-protozoal agents with unexpectedly high potency against Trypanosoma cruzi or Leishmania donovani, and for the treatment of other microbial infections.
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