发明申请
- 专利标题: THIENOPYRIMIDINES
- 专利标题(中): 三苯甲酰亚胺
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申请号: US12937031申请日: 2009-03-23
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公开(公告)号: US20110028472A1公开(公告)日: 2011-02-03
- 发明人: Guenter Hoelzemann , Hartmut Greiner , Christiane Amendt , Frank Zenke
- 申请人: Guenter Hoelzemann , Hartmut Greiner , Christiane Amendt , Frank Zenke
- 申请人地址: DE Darmstadt
- 专利权人: MERCK PATENT CESELLSCHAFT MIT BESCHRANKTER HAFTUNG
- 当前专利权人: MERCK PATENT CESELLSCHAFT MIT BESCHRANKTER HAFTUNG
- 当前专利权人地址: DE Darmstadt
- 优先权: DE102008017853.5 20080409
- 国际申请: PCT/EP2009/002112 WO 20090323
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D495/04 ; A61K31/5377 ; A61P35/00 ; A61P35/04 ; A61P31/18 ; A61P25/28 ; A61P17/02 ; A61P9/10 ; A61P35/02
摘要:
Novel thienopyrimidines of the formula (I), in which R1, R2 and X have the meanings indicated in Claim 1, are inhibitors of TGF-beta receptor kinase, and can be employed, inter alia, for the treatment of tumours.