发明申请
- 专利标题： Inducible Gene Expression
- 专利标题（中）： 诱导基因表达
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申请号： US11658206申请日： 2005-08-03
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公开(公告)号： US20110033429A1公开(公告)日： 2011-02-10
- 发明人: Frank Notka , Ralf Wagner , Diana Hammer
- 申请人： Frank Notka , Ralf Wagner , Diana Hammer
- 优先权： DE102004037611.5 20040803
- 国际申请： PCT/EP05/08427 WO 20050803
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12N15/63 ; C12N5/10 ; A61K35/12 ; A61P31/18
摘要：
The invention relates to vector constructs for an HIV-specific gene therapy. The expression of transgenes is coupled with an infection of the cell with HIV while the transcription of the transgene is controlled by a transcription control region derived from HIV. In addition, the transgene is improved with regard to RNA stability and expression efficiency by modifying the nucleotide sequence.
公开/授权文献
- US08691533B2 Inducible gene expression 公开/授权日：2014-04-08
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