Invention Application
US20110034451A1 TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS
有权
作为PAR1抑制剂的三唑并吡嗪，其生产和用作药物
- Patent Title: TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS
- Patent Title (中): 作为PAR1抑制剂的三唑并吡嗪，其生产和用作药物
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Application No.: US12851189Application Date: 2010-08-05
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Publication No.: US20110034451A1Publication Date: 2011-02-10
- Inventor: Uwe HEINELT , Volkmar WEHNER , Matthias HERRMANN , Karl SCHOENAFINGER , Henning STEINHAGEN , Bodo SCHEIPER
- Applicant: Uwe HEINELT , Volkmar WEHNER , Matthias HERRMANN , Karl SCHOENAFINGER , Henning STEINHAGEN , Bodo SCHEIPER
- Applicant Address: FR Paris
- Assignee: sanofi-aventis
- Current Assignee: sanofi-aventis
- Current Assignee Address: FR Paris
- Priority: EP08290112.5 20080205
- Main IPC: A61K31/538
- IPC: A61K31/538 ; C07D487/04 ; A61K31/5025 ; A61K31/5377 ; A61P7/02 ; A61P9/10 ; A61P9/00 ; A61P11/00 ; A61P9/06 ; A61P29/00 ; A61P3/10 ; A61P35/00 ; A61P35/04
Abstract:
The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R6, R7, R8, Q1, Q2 and Q3 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.
Public/Granted literature
- US08076336B2 Triazolopyridazines as PAR1 inhibitors, production thereof, and use as medicaments Public/Granted day:2011-12-13
Information query
IPC分类:
