Invention Application
US20110034452A1 TRIAZOLIUM SALTS AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS
有权
三唑盐作为PAR1抑制剂，其生产和用作药物
- Patent Title: TRIAZOLIUM SALTS AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS
- Patent Title (中): 三唑盐作为PAR1抑制剂，其生产和用作药物
-
Application No.: US12851219Application Date: 2010-08-05
-
Publication No.: US20110034452A1Publication Date: 2011-02-10
- Inventor: Uwe HEINELT , Volkmar WEHNER , Matthias HERRMANN , Karl SCHOENAFINGER , Henning STEINHAGEN
- Applicant: Uwe HEINELT , Volkmar WEHNER , Matthias HERRMANN , Karl SCHOENAFINGER , Henning STEINHAGEN
- Applicant Address: FR Paris
- Assignee: SANOFI-AVENTIS
- Current Assignee: SANOFI-AVENTIS
- Current Assignee Address: FR Paris
- Priority: EP08290114.1 20080205
- Main IPC: A61K31/536
- IPC: A61K31/536 ; C07D487/04 ; C07D471/04 ; A61K31/5025 ; A61K31/5377 ; A61K31/437 ; A61P7/02 ; A61P29/00 ; A61P9/10 ; A61P9/00 ; A61P11/00 ; A61P9/06 ; A61P3/10 ; A61P35/00 ; A61P35/04
Abstract:
The invention relates to novel compounds of formula I where X, A−, Q1, Q2 Q3, R2, R3, R4, R5, R6, R7, R8 and R9 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.
Public/Granted literature
- US08198272B2 Triazolium salts as PAR1 inhibitors, production thereof, and use as medicaments Public/Granted day:2012-06-12
Information query
