Invention Application
- Patent Title: NITRONE COMPOUNDS, PROCESS OF PREPARATION THEREOF, AND USE THEREOF IN MEDICAMENT MANUFACTURE
- Patent Title (中): 硝基化合物，其制备方法及其在药物制造中的应用
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Application No.: US12937405Application Date: 2009-04-16
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Publication No.: US20110034485A1Publication Date: 2011-02-10
- Inventor: Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
- Applicant: Yuqiang Wang , Jie Jiang , Pei Yu , Yewei Sun , Linda Wang , Zaijun Zhang
- Priority: CN200810027706.1 20080425
- International Application: PCT/CN2009/071312 WO 20090416
- Main IPC: A61K31/505
- IPC: A61K31/505 ; C07D239/30 ; A61P25/00 ; A61P9/00 ; A61P27/02 ; A61P29/00 ; A61P35/00
Abstract:
The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
Public/Granted literature
- US08404688B2 Nitrone compounds, process of preparation thereof, and use thereof in medicament manufacture Public/Granted day:2013-03-26
Information query
