Invention Application
US20110034719A1 PROCESS FOR THE PREPARATION OF (S)- NAPROXEN 4-NITROOXYBUTYL ESTER
审中-公开
制备（S） - 纳洛酮4-硝基丁酯的方法
- Patent Title: PROCESS FOR THE PREPARATION OF (S)- NAPROXEN 4-NITROOXYBUTYL ESTER
- Patent Title (中): 制备（S） - 纳洛酮4-硝基丁酯的方法
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Application No.: US12910550Application Date: 2010-10-22
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Publication No.: US20110034719A1Publication Date: 2011-02-10
- Inventor: Aldo BELLI , Vincenzo CANNATA , Telly FONDUCA , Martin HEDBERG , Andreas WESTERMARK , Marco VILLA
- Applicant: Aldo BELLI , Vincenzo CANNATA , Telly FONDUCA , Martin HEDBERG , Andreas WESTERMARK , Marco VILLA
- Applicant Address: FR Sophia Antipolis-Valbonne
- Assignee: NicOx S.A.
- Current Assignee: NicOx S.A.
- Current Assignee Address: FR Sophia Antipolis-Valbonne
- Priority: SE0103978-3 20011127
- Main IPC: C07C201/02
- IPC: C07C201/02
Abstract:
The present invention relates to a new process for the preparation of the (S)-naproxen 4-nitrooxybutyl ester and to new intermediates obtained and used therein. The invention further relates to the use of the new intermediates for the manufacturing of pharmaceutically active compounds such as (S)-naproxen 4-nitrooxybutyl ester. The invention also relates to the use of (S)-naproxen 4-nitrooxybutyl ester prepared according to the process of the present invention for the manufacturing of a medicament for the treatment of pain.
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