发明申请
- 专利标题: IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF
- 专利标题(中): IL-17同种异体多肽及其治疗用途
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申请号: US12788129申请日: 2010-05-26
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公开(公告)号: US20110038868A1公开(公告)日: 2011-02-17
- 发明人: Jian Chen , Ellen Filvaroff , Audrey Goddard , Austin Gurney , Hanzhong Li , William I. Wood
- 申请人: Jian Chen , Ellen Filvaroff , Audrey Goddard , Austin Gurney , Hanzhong Li , William I. Wood
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61P19/02
摘要:
The present invention is directed to novel polypeptides having sequence identity with IL-17 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders.
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