发明申请
US20110045471A1 Methods for Assaying MC1R Variants and Mitochondrial Markers in Skin Samples
审中-公开
在皮肤样品中测定MC1R变体和线粒体标记物的方法
- 专利标题： Methods for Assaying MC1R Variants and Mitochondrial Markers in Skin Samples
- 专利标题（中）： 在皮肤样品中测定MC1R变体和线粒体标记物的方法
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申请号： US12682338申请日： 2008-09-14
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公开(公告)号： US20110045471A1公开(公告)日： 2011-02-24
- 发明人: Ryan Parr , Mark Birch-Machin , Andrew Harbottle , Robert Thayer , Jennifer Creed , Andrea Maggrah , Kerry Robinson , Gabriel Dakubo , Brian Reguly , Katrina Maki
- 申请人： Ryan Parr , Mark Birch-Machin , Andrew Harbottle , Robert Thayer , Jennifer Creed , Andrea Maggrah , Kerry Robinson , Gabriel Dakubo , Brian Reguly , Katrina Maki
- 申请人地址： CA ON Thunder Bay
- 专利权人： Genesis Genomics Inc.
- 当前专利权人： Genesis Genomics Inc.
- 当前专利权人地址： CA ON Thunder Bay
- 优先权： CAPCT/CA2007/001790 20071011
- 国际申请： PCT/CA08/01801 WO 20080914
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention relates to methods for predicting, diagnosing and monitoring skin states and skin diseases. The methods combine the use of non-invasive skin collecting techniques with one or more assays for determining mitochondrial DNA (mtDNA) aberrations and Melanocortin 1 Receptor (MC1R) variants, thereby providing a comprehensive tool for identifying, predicting and/or monitoring photoageing, ultraviolet radiation (UVR) damage or skin disease. The methods of the invention may also be effective in screening for new therapeutic agents, skin care products and treatment regimes, and may also be useful for monitoring the response of a subject to a preventative or therapeutic treatment.
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